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Chemical Structure : NSC 306711
CAS No.: 813419-93-1
Catalog No.: PC-61207Not For Human Use, Lab Use Only.
NSC 306711 (Ferristatin, NSC306711) is a small-molecule iron transport inhibitor that promotes degradation of the transferrin receptor independent of clathrin and dynamin, is sensitive to the cholesterol-depleting agents filipin and nystatin.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $158 | In stock | |
| 10 mg | $228 | In stock | |
| 25 mg | $388 | In stock | |
| 100 mg | Get quote |
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NSC 306711 (Ferristatin, NSC306711) is a small-molecule iron transport inhibitor that promotes degradation of the transferrin receptor independent of clathrin and dynamin, is sensitive to the cholesterol-depleting agents filipin and nystatin.
| M.Wt | 938.86 | |
| Formula | C32H25Cu2N7O13S3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
(6E)-4-Amino-6-{(2Z)-[4-(3-hydroxy-4-{2-[5-methyl-3-oxo-2-(4-sulfophenyl)-2,3-dihydro-1H-pyrazol-4-yl]hydrazino}phenyl)-6-oxo-2,4-cyclohexadien-1-ylidene]hydrazono}-5-oxo-5,6-dihydro-1,3-naphthalenedi sulfonic acid - copper (1:2) |
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1. Horonchik L, et al. Chem Biol. 2008 Jul 21;15(7):647-53.
2. Lane DJ, et al. Biochem J. 2010 Nov 15;432(1):123-32.
3. Byrne SL, et al. PLoS One. 2013 Jul 23;8(7):e70199.
4. Alkhateeb AA, et al. Am J Physiol Gastrointest Liver Physiol. 2015 Jun 15;308(12):G1019-26.
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