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NSC 65828

Chemical Structure : NSC 65828

CAS No.: 501444-06-0

NSC 65828 (NCI65828)

Catalog No.: PC-70238Not For Human Use, Lab Use Only.

NSC 65828 (NCI65828) is a small-molecule inhibitor of the ribonucleolytic activity of human angiogenin with Ki of 81 uM.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

NSC 65828 (NCI65828) is a small-molecule inhibitor of the ribonucleolytic activity of human angiogenin with Ki of 81 uM; possess antitumor activity in mice.

Physicochemical Properties

M.Wt 419.455
Formula C22H17N3O4S
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

8-amino-5-((4'-hydroxy-[1,1'-biphenyl]-4-yl)diazenyl)naphthalene-2-sulfonic acid

References

1. Kao RY, et al. Proc Natl Acad Sci U S A. 2002 Jul 23;99(15):10066-71.

2. Jenkins JL, et al. Biochemistry. 2003 Jun 10;42(22):6674-87.

3. Seibert C, et al. Virology. 2006 May 25;349(1):41-54.

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