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NSC81111

Chemical Structure : NSC81111

CAS No.: 1678-14-4

NSC81111 (NSC 81111)

Catalog No.: PC-38118Not For Human Use, Lab Use Only.

NSC81111 is a highly potent EGFR-TK inhibitor with IC50 of 0.15 nM.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

NSC81111 is a highly potent EGFR-TK inhibitor with IC50 of 0.15 nM; NSC81111 displays stronger antiproliferative activities than erlotinib with IC50 values of <10 uM overexpressed EGFR-TK cancer cell lines: A431 and HeLa.

Physicochemical Properties

M.Wt 308.333
Formula C19H16O4
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

References

1. Jiwacharoenchai N, et al. Bioorg Med Chem Lett. 2022 Feb 15;58:128524.

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