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NSUN2 inhibitor AK

Chemical Structure : NSUN2 inhibitor AK

CAS No.:

NSUN2 inhibitor AK (AK-968/36977265)

Catalog No.: PC-26591Not For Human Use, Lab Use Only.

NSUN2 inhibitor AK (AK-968/36977265) is a small molecule inhibitor of RNA methyltransferase NSUN2, decreases m5C occupancy and GATM mRNA levels, shows anti-fibrotic efficacy.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

NSUN2 inhibitor AK (AK-968/36977265) is a small molecule inhibitor of RNA methyltransferase NSUN2, decreases m5C occupancy and GATM mRNA levels, shows anti-fibrotic efficacy.

Physicochemical Properties

M.Wt 339.36
Formula C17H17N5O3
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(E)-2-(4-amino-3-cyano-1-(2-hydroxyethyl)-1H-pyrazol-5-yl)-3-(2,5-dimethoxyphenyl)prop-2-enenitrile

References

1. Suo X, et al. Cell Rep. 2026 Apr 16;45(4):117253.

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