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Chemical Structure : NU-8231
Catalog No.: PC-60437Not For Human Use, Lab Use Only.
NU-8231 is a small molecule inhibitor of MDM2-p53 protein-protein interaction with IC50 of 5.3 uM in ELISA assay.
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NU-8231 is a small molecule inhibitor of MDM2-p53 protein-protein interaction with IC50 of 5.3 uM in ELISA assay.
NU-8231 induces p53-dependent gene transcription SJSA human sarcoma cell line.
| M.Wt | 467.95 | |
| Formula | C26H26ClNO5 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Hardcastle IR, et al. Bioorg Med Chem Lett. 2005 Mar 1;15(5):1515-20.
2. Hardcastle IR, et al. J Med Chem. 2011 Mar 10;54(5):1233-43.
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