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NV914

Chemical Structure : NV914

CAS No.: 2341941-41-9

NV914 (NV 914)

Catalog No.: PC-20935Not For Human Use, Lab Use Only.

NV914 is a small molecule inhibitor of tRNA-specific 2′-O-methyltransferase (FTSJ1), exerts readthrough activity in vitro and in vivo.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

NV914 is a small molecule inhibitor of tRNA-specific 2′-O-methyltransferase (FTSJ1), exerts readthrough activity in vitro and in vivo.

Physicochemical Properties

M.Wt 445.18
Formula C15HF10N3O2
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

O=C(NC1=NOC(C2=C(F)C(F)=C(F)C(F)=C2F)=N1)C3=C(F)C(F)=C(F)C(F)=C3F

References

1. Carollo PS, et al Int J Mol Sci. 2023 Jun 1;24(11):9609. .

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