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NW1028

Chemical Structure : NW1028

CAS No.: 2749599-78-6

NW1028 (NW 1028)

Catalog No.: PC-49107Not For Human Use, Lab Use Only.

NW1028 is a small molecule that target the regulatory domain of VCP/p97, inhibits the degradation of a p97-dependent reporter, does not affect the main catalytic domain of p97.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

NW1028 is a small molecule that target the regulatory domain of VCP/p97, inhibits the degradation of a p97-dependent reporter, does not affect the main catalytic domain of p97.

Physicochemical Properties

M.Wt 415.468
Formula C19H21N5O4S
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(S)-1-((4-oxo-2-thioxo-1,2,3,4-tetrahydroquinazoline-7-carbonyl)-L-prolyl)pyrrolidine-2-carboxamide

References

1. Ainoa Figuerola-Conchas, et al. ACS Chem Biol. 2020 Jan 17;15(1):243-253.

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