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Nek2 inhibitor 72

Chemical Structure : Nek2 inhibitor 72

CAS No.:

Nek2 inhibitor 72

Catalog No.: PC-61479Not For Human Use, Lab Use Only.

A potent, ATP-competitive and relative selective Nek2 inhibitor with IC50 of 0.27 uM.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

A potent, ATP-competitive and relative selective Nek2 inhibitor with IC50 of 0.27 uM; displays >10-fold selectivity over CDK2.

Physicochemical Properties

M.Wt 334.427
Formula C19H22N6
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name

(E)-6-(2-(azepan-1-yl)vinyl)-N-phenyl-9H-purin-2-amine

References

1. Coxon CR, et al. Oncotarget. 2017 Mar 21;8(12):19089-19124.

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