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Chemical Structure : Nizubaglustat
Catalog No.: PC-20061Not For Human Use, Lab Use Only.
Nizubaglustat is a potent, selective inhibitor of glucosylceramide synthase (GCS) with IC50 of 25 nM, inhibits acid glucosylceramidase (GBA1) and neutral glucosylceramidase (GBA2) with IC50 of 200 and 0.08 nM, respectively.
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Nizubaglustat is a potent, selective inhibitor of glucosylceramide synthase (GCS) with IC50 of 25 nM, inhibits acid glucosylceramidase (GBA1) and neutral glucosylceramidase (GBA2) with IC50 of 200 and 0.08 nM, respectively.
| M.Wt | 433.52 | |
| Formula | C24H32FNO5 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Amar T Ghisaidoobe, et al. J Med Chem. 2014 Nov 13;57(21):9096-104.
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