OGG1 agonist F51

Chemical Structure : OGG1 agonist F51

Catalog No.: PC-27343Not For Human Use, Lab Use Only.

OGG1 agonist F51 is a potent small-molecule agonist, protects against PQ-induced cytotoxicity in Kasumi-1 cells, binds to catalytic-site rather than allosteric binding.

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Biological Activity

OGG1 agonist F51 is a potent small-molecule agonist, protects against PQ-induced cytotoxicity in Kasumi-1 cells, binds to catalytic-site rather than allosteric binding.

Physicochemical Properties

M.Wt	347.24
Formula	C18H16Cl2N2O
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	1-(2-(benzyloxy)-2-(2,4-dichlorophenyl)ethyl)-1H-imidazole

References

1. Luzadder, M. M. et al. Luzadder, M. M. et al. Small molecule agonists of 8-oxoguanine DNA glycosylase, OGG1. bioRXiv (2026).

2. Syed A, et al. Nat Commun. 2026 Jul 15. doi: 10.1038/s41467-026-75471-1.

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OGG1 agonist F51

Biological Activity

Physicochemical Properties

References

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