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OGT inhibitor 4a

Chemical Structure : OGT inhibitor 4a

CAS No.:

OGT inhibitor 4a (OSMI-4 active form)

Catalog No.: PC-35722Not For Human Use, Lab Use Only.

OGT inhibitor 4a (OSMI-4 active form) is a novel potent, selective O-linked N-acetylglucosamine transferase (OGT) inhibitor with Kd of 8 nM, the active form of OSMI-4..

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

OGT inhibitor 4a (OSMI-4 active form) is a novel potent, selective O-linked N-acetylglucosamine transferase (OGT) inhibitor with Kd of 8 nM, the active form of OSMI-4.

Physicochemical Properties

M.Wt 576.035
Formula C25H22ClN3O7S2
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(R)-N-(2-((7-chloro-2-oxo-1,2-dihydroquinoline)-6-sulfonamido)-2-(2-methoxyphenyl)acetyl)-N-(thiophen-2-ylmethyl)glycine

References

1. Martin SES, et al. J Am Chem Soc. 2018 Oct 24;140(42):13542-13545.

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