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Chemical Structure : OSI-420
CAS No.: 183320-51-6
Catalog No.: PC-43436Not For Human Use, Lab Use Only.
OSI-420 (Desmethyl Erlotinib, CP-473420) is an active metabolite of erlotinib, which is a potent EGFR tyrosin kinase inhibitor for treatment of NSCLC..
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $118 | In stock | |
| 10 mg | $188 | In stock | |
| 50 mg | $398 | In stock | |
| 100 mg | Get quote |
Bulk size, bulk discount!
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OSI-420 (Desmethyl Erlotinib, CP-473420) is an active metabolite of erlotinib, which is a potent EGFR tyrosin kinase inhibitor for treatment of NSCLC.
| M.Wt | 415.87 | |
| Formula | C21H22ClN3O4 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
DMSO: ≥ 4.2 mg/mL |
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| Chemical Name/SMILES |
Ethanol, 2-[[4-[(3-ethynylphenyl)amino]-7-(2-methoxyethoxy)-6-quinazolinyl]oxy]-, hydrochloride (1:1) |
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1. Broniscer A, et al. Clin Cancer Res. 2007 Mar 1;13(5):1511-5.
2. Meany HJ, et al. Cancer Chemother Pharmacol. 2008 Aug;62(3):387-92.
3. Togashi Y, et al. J Thorac Oncol. 2010 May;5(5):601-5.
4. Flaig TW, et al. Br J Cancer. 2010 Sep 7;103(6):796-801.
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