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Chemical Structure : OU749
CAS No.: 519170-13-9
Catalog No.: PC-22154Not For Human Use, Lab Use Only.
OU749 is a potent, species-specific inhibitor of human gamma-glutamyl transpeptidase (GGT) with Ki of 17.6 uM.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $88 | In stock | |
| 10 mg | $128 | In stock | |
| 25 mg | $198 | In stock | |
| 50 mg | Get quote | ||
| 100 mg | Get quote |
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OU749 is a potent, species-specific inhibitor of human gamma-glutamyl transpeptidase (GGT) with Ki of 17.6 uM.
OU749 is a competitive inhibitor of the acceptor glycyl-glycine, occupies the acceptor site while binding to the gamma-glutamyl substrate complex.
OU749 is more than 150-fold less toxic than the GGT inhibitor acivicin toward dividing cells.
OU749 is species-specific, inhibiting GGT isolated from human kidney with 7-10-fold greater potency than GGT isolated from rat or mouse kidney.
OU749 does not inhibit GGT from pig cells.
| M.Wt | 361.43 | |
| Formula | C16H15N3O3S2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
N-[5-[(4-Methoxyphenyl)methyl]-1,3,4-thiadiazol-2-yl]benzenesulfonamide |
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1. King JB, et al. J Biol Chem. 2009 Apr 3;284(14):9059-65.
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