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Chemical Structure : OX03050
Catalog No.: PC-60631Not For Human Use, Lab Use Only.
A novel potent, competitive squalene synthase inhibitor that upregulate the LDLR in mouse and human liver cell lines with EC50 of 26 nM.
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A novel potent, competitive squalene synthase inhibitor that upregulate the LDLR in mouse and human liver cell lines with EC50 of 26 nM; exhibits much-improved pharmacokinetic profile and shows in vivo efficacy compared with OX03771.
| M.Wt | 254.329 | |
| Formula | C17H18O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Kerr AG, et al. J Pharmacol Exp Ther. 2017 Jun;361(3):417-428.
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