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Olmesartan

Chemical Structure : Olmesartan

CAS No.: 144689-24-7

Olmesartan (RNH-6270, CS-088, CS088)

Catalog No.: PC-45130Not For Human Use, Lab Use Only.

Olmesartan (RNH-6270, CS-088) is a potent, selective angiotensin II receptor antagonist, inhibits [125I]angiotensin II binding to bovine adrenal cortical membranes (angiotensin AT1 receptors) with IC50 of 7.7 nM.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Olmesartan (RNH-6270, CS-088) is a potent, selective angiotensin II receptor antagonist, inhibits [125I]angiotensin II binding to bovine adrenal cortical membranes (angiotensin AT1 receptors) with IC50 of 7.7 nM.

Physicochemical Properties

M.Wt 446.5016
Formula C24H26N6O3
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

DMSO: ≥ 55 mg/mL

Chemical Name/SMILES

1H-Imidazole-5-carboxylic acid, 4-(1-hydroxy-1-methylethyl)-2-propyl-1-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-

References

1. Mizuno M, et al. Eur J Pharmacol. 1995 Oct 16;285(2):181-8.

2. Kim S, et al. Hypertens Res. 1997 Jun;20(2):133-42.

3. Takemoto M, et al. Hypertension. 1997 Dec;30(6):1621-7.

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