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Chemical Structure : Ombrabulin
Catalog No.: PC-70178Not For Human Use, Lab Use Only.
A novel combretastatin A-4 derivative and tubulin polymerization inhibitor that strongly stanches tumour blood flows and inhibits growth of tumours developing in various tissues and organ.
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A novel combretastatin A-4 derivative and tubulin polymerization inhibitor that strongly stanches tumour blood flows and inhibits growth of tumours developing in various tissues and organ; a vascular-disrupting agent under clinical investigation combined with cisplatin/docetaxel or carboplatin/paclitaxel in patients with advanced solid tumors.
Chemotherapeutic Agents
Phase 2 Clinical
| M.Wt | 402.45 | |
| Formula | C21H26N2O6 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Kim TJ, et al. Cancer Res. 2007 Oct 1;67(19):9337-45.
2. Hori K, et al. Cancer Sci. 2008 Jul;99(7):1485-91.
3. Hori K, et al. Br J Cancer. 2002 May 20;86(10):1604-14.
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