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Chemical Structure : Org 25543
CAS No.: 495076-64-7
Catalog No.: PC-60445Not For Human Use, Lab Use Only.
Org 25543 is a potent, highly selective glycine transporter 1 (GlyT2) inhibitor with IC50 of 16 nM with negligible affinity for GlyT1.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $228 | In stock | |
| 10 mg | $368 | In stock | |
| 25 mg | $548 | In stock | |
| 50 mg | Get quote | ||
| 100 mg | Get quote |
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Org 25543 is a potent, highly selective glycine transporter 1 (GlyT2) inhibitor with IC50 of 16 nM with negligible affinity for GlyT1.
| M.Wt | 448.988 | |
| Formula | C24H33ClN2O4 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
Benzamide, N-[[1-(dimethylamino)cyclopentyl]methyl]-3,5-dimethoxy-4-(phenylmethoxy)-, monohydrochloride (9CI) |
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1. Morita K, et al. J Pharmacol Exp Ther. 2008 Aug;326(2):633-45.
2. Rousseau F, et al. J Neurosci. 2008 Sep 24;28(39):9755-68.
3. Romei C, et al. J Neurochem. 2011 Oct;119(1):50-63.
4. Mingorance-Le Meur A, et al. Br J Pharmacol. 2013 Nov;170(5):1053-63.
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