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Chemical Structure : Otamixaban
CAS No.: 193153-04-7
Catalog No.: PC-45940Not For Human Use, Lab Use Only.
A potent and selective factor Xa (FXa) inhibitor with Ki of 0.4 nM.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 100 mg | $987.2 | In stock |
Bulk size, bulk discount!
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A potent and selective factor Xa (FXa) inhibitor with Ki of 0.4 nM; shows >1,000-fold selectivity over thrombin, activated protein C (aPC), plasmin, and tissue-plasminogen activator (t-PA); dose-dependently prolongs the time to vessel occlusion and inhibits thrombus formation in canine models of thrombosis.
Thrombosis
Phase 3 Discontinued
| M.Wt | 446.4984 | |
| Formula | C25H26N4O4 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
Benzenepropanoic acid, 3-(aminoiminomethyl)-.alpha.-[(1R)-1-[[4-(1-oxido-4-pyridinyl)benzoyl]amino]ethyl]-, methyl ester, (.alpha.R)- |
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1. Guertin KR, et al. Bioorg Med Chem Lett. 2002 Jun 17;12(12):1671-4.
2. Chu V, et al. Thromb Res. 2001 Aug 15;103(4):309-24.
3. Rebello SS, et al. J Cardiovasc Pharmacol. 2001 Aug;38(2):288-97.
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