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Chemical Structure : P11
Catalog No.: PC-62386Not For Human Use, Lab Use Only.
PAFAH inhibitor P11 (P11) is a potent, selective platelet-activating factor acetylhydrolases PAFAH1b2 and PAFAH1b3 inhibitor with IC50 of 40 nM and 900 nM respectively.
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PAFAH inhibitor P11 (P11) is a potent, selective platelet-activating factor acetylhydrolases PAFAH1b2 and PAFAH1b3 inhibitor with IC50 of 40 nM and 900 nM respectively; blocks PAFAH1b2- and PAFAH1b3-mediated hydrolysis of the substrate PAF to lyso-PAF with IC50 values of 36 nM and 880 nM; impairs tumor cell survival; in situ-active and can be used to investigate the cellular functions of PAFAH1b2/3.
| M.Wt | 503.7 | |
| Formula | C30H33NO4S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Chang JW, et al. ACS Chem Biol. 2015 Apr 17;10(4):925-32.
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