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P7C3

Chemical Structure : P7C3

CAS No.: 301353-96-8

P7C3 (NAMPT activator P7C3)

Catalog No.: PC-47022Not For Human Use, Lab Use Only.

P7C3 is an aminopropyl carbazole having proneurogenic and neuroprotective properties, protects newborn neurons from apoptotic cell death, binds to and activates nicotinamide phosphoribosyltransferase (NAMPT).

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Biological Activity

P7C3 is an aminopropyl carbazole having proneurogenic and neuroprotective properties, protects newborn neurons from apoptotic cell death, binds to and activates nicotinamide phosphoribosyltransferase (NAMPT).

Physicochemical Properties

M.Wt 474.196
Formula C21H18Br2N2O
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

3,6-Dibromo-alpha-[(phenylamino)methyl]-9H-carbazole-9-ethanol

References

1. Pieper AA, et al. Cell. 2010 Jul 9;142(1):39-51.

2. Wang G, et al. Cell. 2014 Sep 11;158(6):1324-1334.

3. MacMillan KS, et al. J Am Chem Soc. 2011 Feb 9;133(5):1428-37.

4. Tesla R, et al. Proc Natl Acad Sci U S A. 2012 Oct 16;109(42):17016-21.

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