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Chemical Structure : PBI-4050 sodium
CAS No.: 1254472-97-3
Catalog No.: PC-35465Not For Human Use, Lab Use Only.
PBI-4050 (Setogepram, Fezagepras) sodium is a synthetic analog of a medium-chain fatty acid that displays agonist and antagonist ligand affinity toward GPR40 and GPR84, respectively.
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|---|---|---|---|
| 5 mg | $158 | In stock | |
| 10 mg | $248 | In stock | |
| 25 mg | $398 | In stock | |
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PBI-4050 (Setogepram, Fezagepras) sodium is a synthetic analog of a medium-chain fatty acid that displays agonist and antagonist ligand affinity toward GPR40 and GPR84, respectively.
PBI-4050 significantly attenuated fibrosis in many injury contexts, as evidenced by the antifibrotic activity observed in kidney, liver, heart, lung, pancreas, and skin fibrosis models.
PBI-4050 is a first-in-class compound that may be effective for managing inflammatory and fibrosis-related diseases.
| M.Wt | 229.275 | |
| Formula | C13H18NaO2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
2-(3-pentylphenyl)acetic acid, sodium salt |
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1. Gagnon L, et al. Am J Pathol. 2018 May;188(5):1132-1148.
2. Li Y, et al. JCI Insight. 2018 May 17;3(10). pii: 120365.
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