PDL103 | Dual FXR/GPBAR1 antagonist | Probechem Biochemicals

Chemical Structure : PDL103

Catalog No.: PC-20484Not For Human Use, Lab Use Only.

PDL103 is a potent, dual FXR/GPBAR1 antagonist with IC50 of 10 and 19 uM, respectively.

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Biological Activity

PDL103 is a potent, dual FXR/GPBAR1 antagonist with IC50 of 10 and 19 uM, respectively.

M.Wt	426.29
Formula	C23H17Cl2NO3
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(4'-((3-(2,6-dichlorophenyl)isoxazol-5-yl)methoxy)-[1,1'-biphenyl]-4-yl)methanol

1. Di Giorgio C, et al. Front Oncol. 2023 Mar 14;13:1140730.