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PDMP hydrochloride

Chemical Structure : PDMP hydrochloride

CAS No.: 73257-80-4

PDMP hydrochloride

Catalog No.: PC-61425Not For Human Use, Lab Use Only.

A ceramide analog that inhibits glucosylceramide synthase (GCS), reduces the synthesis of sphingosine and its derivatives, increases cellular ceramide, and induces cell cycle arrest. .

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

A ceramide analog that inhibits glucosylceramide synthase (GCS), reduces the synthesis of sphingosine and its derivatives, increases cellular ceramide, and induces cell cycle arrest.

Physicochemical Properties

M.Wt 427
Formula C23H38N2O3 • HCl
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

Decanamide, N-[2-hydroxy-1-(4-morpholinylmethyl)-2-phenylethyl]-, hydrochloride (9CI)

References

1. Abe A, et al. J Lipid Res. 1995 Mar;36(3):611-21.

2. Rani CS, et al. J Biol Chem. 1995 Feb 10;270(6):2859-67.

3. Bielawska A, et al. J Biol Chem. 1996 May 24;271(21):12646-54.

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