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Chemical Structure : PF-06305591
CAS No.: 1449473-97-5
Catalog No.: PC-35885Not For Human Use, Lab Use Only.
PF-06305591 (PF06305591) is a potent, highly selective selective NaV1.8 blocker with IC50 of 15 nM, displays no significant activity against other sodium channel subtypes, K+ channels and Ca2+ channels.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $158 | In stock | |
| 25 mg | $278 | In stock | |
| 50 mg | $488 | In stock | |
| 100 mg | Get quote |
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PF-06305591 (PF06305591) is a potent, highly selective selective NaV1.8 blocker with IC50 of 15 nM, displays no significant activity against other sodium channel subtypes, K+ channels and Ca2+ channels.
PF-06305591 displays excellent preclinical in vitro ADME and safety profile.
| M.Wt | 274.368 | |
| Formula | C15H22N4O | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
(2R,3S)-3-amino-3-(5-(tert-butyl)-1H-benzo[d]imidazol-2-yl)-2-methylpropanamide |
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1. Brown AD, et al. Bioorg Med Chem. 2019 Jan 1;27(1):230-239.
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