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Chemical Structure : PF-06807656
Catalog No.: PC-63348Not For Human Use, Lab Use Only.
PF-06807656 is a potent, selective renal outer medullary potassium channel (ROMK, Kir1.1a) inhibitor with IC50 of 61 nM for hROMK in patch-clamp assays.
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PF-06807656 is a potent, selective renal outer medullary potassium channel (ROMK, Kir1.1a) inhibitor with IC50 of 61 nM for hROMK in patch-clamp assays.
PF-06807656 is highly selective for inhibition of human over rat ROMK and to be insensitive to the N171D pore mutation.
| M.Wt | 449.91 | |
| Formula | C19H20ClN5O4S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Sammons MF, et al. ACS Med Chem Lett. 2018 Jan 19;9(2):125-130.
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