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PKMYT1 inhibitor XH-30

Chemical Structure : PKMYT1 inhibitor XH-30

CAS No.: 3077136-87-6

PKMYT1 inhibitor XH-30

Catalog No.: PC-26008Not For Human Use, Lab Use Only.

PKMYT1 inhibitor XH-30 is a highly potent PKMYT1 inhibitor with IC50 of 4.1 nM, suppresses the proliferation of the MDA-MB-231 (P53-mutated TNBC cell line) with IC50 of 1.85 uM, demonstrates antitumor effects in vivo.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

PKMYT1 inhibitor XH-30 is a highly potent PKMYT1 inhibitor with IC50 of 4.1 nM, suppresses the proliferation of the MDA-MB-231 (P53-mutated TNBC cell line) with IC50 of 1.85 uM, demonstrates antitumor effects in vivo.

Physicochemical Properties

M.Wt 337.38
Formula C19H19N3O3
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

6-Amino-2-cyclopropyl-7-(3-hydroxy-2,6-dimethylphenyl)benzo[d]oxazole-5-carboxamide

References

1. Jingling Huang, et al. J Med Chem. 2026 Jan 8;69(1):228-249.

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