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Chemical Structure : PKN3 inhibitor 16
Catalog No.: PC-38564Not For Human Use, Lab Use Only.
PKN3 inhibitor 16 is a potent, cell active protein kinase novel 3 (PKN3) inhibitor with biochemical IC50 of 14 nM, celluar IC50 of 1.3 uM.
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PKN3 inhibitor 16 is a potent, cell active protein kinase novel 3 (PKN3) inhibitor with biochemical IC50 of 14 nM, celluar IC50 of 1.3 uM.
PKN3 presents a useful potential tool compound to study the biology of PKN3 including links to pancreatic and prostate cancer, along with T-cell acute lymphoblastic leukemia.
Protein kinase N (PKN, protein kinase novel) family genes encode for the three isoforms PKN1 (PKNα/PRK1/PAK1), PKN2 (PKNγ/PRK2/PAK2/) and PKN3 (PKNβ) that form the subfamily of AGC serine/threonine protein kinases.
| M.Wt | 436.249 | |
| Formula | C18H17IN2O3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Asquith CRM, et al. ChemMedChem. 2022 Apr 11.
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