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PKSI-527

Chemical Structure : PKSI-527

CAS No.: 128837-71-8

PKSI-527

Catalog No.: PC-25748Not For Human Use, Lab Use Only.

PKSI-527 is a highly selective plasma kallikrein inhibitor, suppresses collagen-induced arthritis (CIA) by modifying the kallikrein-kinin system, also is a selective PLK inhibitor.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

PKSI-527 is a highly selective plasma kallikrein inhibitor, suppresses collagen-induced arthritis (CIA) by modifying the kallikrein-kinin system, also is a selective PLK inhibitor.

Physicochemical Properties

M.Wt 474.00
Formula C25H32ClN3O4
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

2-(4-((S)-2-(trans-4-(Aminomethyl)cyclohexane-1-carboxamido)-3-phenylpropanamido)phenyl)acetic acid hydrochloride

References

1. Marangoni RA, et al. Peptides. 2006 Jul;27(7):1770-5.

2. Zhu J, et al. Immunopharmacol Immunotoxicol. 2018 Apr;40(2):134-148.

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