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Chemical Structure : POL5551
Catalog No.: PC-61289Not For Human Use, Lab Use Only.
A novel peptidic, potent and highly selective CXCR4 antagonist with IC50 of 1.7 nM.
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A novel peptidic, potent and highly selective CXCR4 antagonist with IC50 of 1.7 nM; displays about 200-fold lower than Plerixafor (IC50=400-600 nM), and mobilizes hematopoietic stem and progenitor cells (HSPCs) with greater efficiency than Plerixafor, does not induce major morphological changes in the BM of mice; reduces the migration of breast cancer cells in vitro, and reduces metastasis and prolongs survival in mice.
HIV Infection
Discontinued
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| Appearance | Solid | |
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| Solubility |
10 mM in DMSO |
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