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Chemical Structure : PP1 inhibitor C31
Catalog No.: PC-35687Not For Human Use, Lab Use Only.
PP1 inhibitor C31 is a 1E7-03 analog and protein phosphatase 1 (PP1) targeting small molecule with Kd of 1.88 uM, inhibits Ebola virus (EBOV) transcription and replication.
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PP1 inhibitor C31 is a 1E7-03 analog and protein phosphatase 1 (PP1) targeting small molecule with Kd of 1.88 uM, inhibits Ebola virus (EBOV) transcription and replication.
PP1 inhibitor C31 binds to the PP1 C-terminal groove in vitro and increased VP30 phosphorylation in cultured cells, also inhibits EBOV minigenome.
PP1 inhibitor C31 is a novel PP1-targeting EBOV inhibitor with improved pharmacological properties.
| M.Wt | 475.501 | |
| Formula | C26H25N3O6 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Ammosova T, et al. J Infect Dis. 2018 Aug 28. doi: 10.1093/infdis/jiy422.
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