Welcome to Shanghai Probechem Biochemicals Co Ltd !Global Supplier of Chemical Probes, Inhibitors & Agonists.
Chemical Structure : PP5 inhibitor P053
Catalog No.: PC-21296Not For Human Use, Lab Use Only.
PP5 inhibitor P053 (Compound P053) is a potent, selective and competitive inhibitor of serine/threonine protein phosphatase-5 (PP5) with Ki of 244 nM, specifically binds and inhibits PP5 activity.
Bulk size, bulk discount!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
PP5 inhibitor P053 (Compound P053) is a potent, selective and competitive inhibitor of serine/threonine protein phosphatase-5 (PP5) with Ki of 244 nM, specifically binds and inhibits PP5 activity.
PP5 inhibitor P053 does not bind to PP2A.
PP5 inhibitor P053 significantly inhibits cell proliferation in VHL-null ccRCC cells, 786-O and A498 compared to normal epithelial renal cell HK2 as well as VHL-positive ccRCC cell lines Caki-1 and Caki-2.
PP5 inhibitor P053 induces extrinsic apoptosis in clear cell renal cell carcinoma.
| M.Wt | 342.41 | |
| Formula | C18H18N2O3S | |
| Appearance | Solid | |
| Storage |
|
|
| Solubility |
10 mM in DMSO |
|
1. Ahanin EF, et al. Cell Chem Biol. 2023 Oct 19;30(10):1223-1234.e12.
Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright
