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PRX-08066

Chemical Structure : PRX-08066

CAS No.: 866206-54-4

PRX-08066 (PRX08066)

Catalog No.: PC-27115Not For Human Use, Lab Use Only.

PRX-08066 is a potent, selective 5-HT2B receptor (5-HT2BR) antagonist with Ki of 3.4 nM, causes selective vasodilation of pulmonary arteries.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

PRX-08066 is a potent, selective 5-HT2B receptor (5-HT2BR) antagonist with Ki of 3.4 nM, causes selective vasodilation of pulmonary arteries.

Physicochemical Properties

M.Wt 401.89
Formula C19H17ClFN5S
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

5-((4-((6-Chlorothieno[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)methyl)-2-fluorobenzonitrile

References

1. Porvasnik SL, et al. J Pharmacol Exp Ther. 2010 Aug;334(2):364-72.

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