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PS3061

Chemical Structure : PS3061

CAS No.: 2377739-98-3

PS3061 (PS 3061, PS-3061)

Catalog No.: PC-21749Not For Human Use, Lab Use Only.

PS3061 (PS 3061) is a substrate-selective co-translational translocation inhibitor, modulates SEC61 translocon and inhibits both DENV and ZIKV virion production and replication.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    PS3061 (PS 3061) is a substrate-selective co-translational translocation inhibitor, modulates SEC61 translocon and inhibits both DENV and ZIKV virion production and replication.

    Physicochemical Properties

    M.Wt 1032.14
    Formula C53H75BrN8O8
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20°C 12 Months; 4°C 6 Months
    In Solvent
    -80°C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    3-((2R,5S,8S,14S,17S,20S)-14-((1-(4-bromobenzyl)-1H-indol-3-yl)methyl)-5,8,11,17-tetraisobutyl-7,13,19,20-tetramethyl-3,6,9,12,15,18,21-heptaoxo-1-oxa-4,7,10,13,16,19-hexaazacyclohenicosan-2-yl)propanenitrile

    References

    1. Priya S Shah, et al. Cell. 2018 Dec 13;175(7):1931-1945.e18.

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