| Cat. No. |
Product Name |
Information |
| PC-20177 |
JNJ-1802
DENV inhibitor
|
JNJ-1802 (Mosnodenvir) is a highly potent, pan-serotype dengue virus (DENV) inhibitor (EC50=0.04 nM-1.8 nM), blocks the NS3-NS4B interaction within the viral replication complex (EC50=1.4 nM, DENV-2). |
| PC-49197 |
U18666A
NPC1 inhibitor
|
U18666A is a cationic sterol that blocks the movement of cholesterol out of lysosomes and also inhibits Ebola virus infections, targets niemann-Pick C1 (NPC1) which exports cholesterol derived from receptor-mediated uptake of LDL, and mediates cellular entry of Ebola virus. |
| PC-47063 |
RK-0404678
DENV2 RdRp inhibitor
|
RK-0404678 is a potent, small molecule inhibitor of DENV type 2 (DENV2) RdRp activities, exhibits in cellulo antiviral EC50 of 6.0 uM for DENV2. |
| PC-72500 |
JNJ-A07
DENV inhibitor
|
JNJ-A07 is a highly potent, highly specific dengue virus (DENV) inhibitor targeting the NS3-NS4B interaction. |
| PC-35947 |
JBJ-01-162-04
DENV inhibitor
|
JBJ-01-162-04 is a small molecule targeting the flavivirus E protein with broad-spectrum activity, shows activity against DENV in the infectivity assay with IC90 of 0.1 uM. |
| PC-35651 |
ZIKV inhibitor K22
|
ZIKV inhibitor K22 is a small molecule that exerts a potent antiviral activity against a broad range of coronaviruses by targeting membrane-bound viral RNA replication, effectively inhibits ZIKV with IC50 of 2.1 uM (48 h p.i). |
| PC-35010 |
IHVR-19029
ER α-glucosidase inhibitor
|
IHVR-19029 is a novel antiviral compound that acts as ER α-glucosidase inhibitor, synergistically inhibits the replication of Yellow fever and Ebola viruses in cultured cells combined with favipiravir (T-705). |
| PC-60960 |
MK-0608
HCV inhibitor
|
MK-0608 is a nucleoside analogue that shows potent inhibition for replication of several mosquito-borne flaviviruses including DENV and ZIKV. |
| PC-60313 |
GS-5734
SARS-CoV-2 inhibitor
|
GS-5734 (Remdesivir) is a monophosphoramidate prodrug of adenosine analogue that exhibits antiviral activity against multiple variants of EBOV (EC50=70-140 nM) and other filoviruses (EC50=0.019-1.48 uM) in cell-based assays. |
| PC-22064 |
ARDP0006
DENV inhibitor
|
ARDP0006 is a potent inhibitor of dengue virus (DENV) NS2B-NS3 protease with EC50 of 4.2 uM. |
| PC-22063 |
DV-B-120
DENV inhibitor
|
DV-B-120 is a potent inhibitor of dengue virus (DENV) NS2B-NS3 protease, demonstrates superior inhibition of NS2B-NS3 protease activity and lower toxicity compared to ARDP0006. |
| PC-21967 |
Arbemnifosbuvir
DENV inhibitor
|
Arbemnifosbuvir (AT-752) a double prodrug of a guanosine nucleotide analog with activity against dengue virus (DENV), potently inhibits DENV1-4 with EC50 of 0.5 uM in Huh-7 cells, inhibits NS5 active site of all four DENV1-4 NS5 RdRps. |
