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Chemical Structure : PSB-CB5
Catalog No.: PC-49028Not For Human Use, Lab Use Only.
PSB-CB5 is a potent, selective antagonist of GPR18, inhibits GPR18 activation by tetrahydrocannabinol (THC) with IC50 of 279 nM in β-arrestin recruitment assays.
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PSB-CB5 is a potent, selective antagonist of GPR18, inhibits GPR18 activation by tetrahydrocannabinol (THC) with IC50 of 279 nM in β-arrestin recruitment assays.
PSB-CB5 exhibits >36-fold selectivity versus CB1 and GPR55 and 14-fold selectivity versus CB2 receptors.
PSB-CB5 inhibits N-Arachidonylglycine induced acrosomal exocytosis in human spermatozoa.
| M.Wt | 384.878 | |
| Formula | C20H17ClN2O2S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Schoeder CT, et al. Eur J Med Chem. 2018 Jul 15;155:381-397.
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