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Chemical Structure : PSI-6130
CAS No.: 817204-33-4
Catalog No.: PC-42412Not For Human Use, Lab Use Only.
PSI-6130 (R-1656) is a potent, specific inhibitor of HCV RNA synthesis by inhibiting the NS5B RNA polymerase (EC90=4.6 uM in replicon assay).
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 25 mg | $258 | In stock | |
| 100 mg | $758 | In stock | |
| 1 g | Get quote |
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PSI-6130 (R-1656) is a potent, specific inhibitor of HCV RNA synthesis by inhibiting the NS5B RNA polymerase (EC90=4.6 uM in replicon assay).
PSI-6130 shows no anti-BVDV activity and weak antiviral activity against other flaviviruses, including West Nile virus, Dengue type 2, and yellow fever virus.
PSI-6130 has little or no cytotoxicity against various cell type.
| M.Wt | 259.2343 | |
| Formula | C10H14FN3O4 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
Cytidine, 2'-deoxy-2'-fluoro-2'-methyl-, (2'R)- |
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1. Clark JL, et al. J Med Chem. 2005 Aug 25;48(17):5504-8.
2. Murakami E, et al. Antimicrob Agents Chemother. 2007 Feb;51(2):503-9.
3. Stuyver LJ, et al. Antivir Chem Chemother. 2006;17(2):79-87.
4. Ma H, et al. J Biol Chem. 2007 Oct 12;282(41):29812-20.
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