PTPRO-IN-1 | PTPRO inhibitor | Probechem Biochemicals

Chemical Structure : PTPRO-IN-1

PTPRO-IN-1 (Compound 30k)

Catalog No.: PC-28602Not For Human Use, Lab Use Only.

PTPRO-IN-1 (Compound 30k) is a potent and selective inhibitor of protein tyrosine phosphatase receptor type O (PTPRO) with IC50 of 0.16 uM, suppresses IL-6 via NF-κB pathway modulation in macrophages.

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Biological Activity

PTPRO-IN-1 (Compound 30k) is a potent and selective inhibitor of protein tyrosine phosphatase receptor type O (PTPRO) with IC50 of 0.16 uM, suppresses IL-6 via NF-κB pathway modulation in macrophages.

Physicochemical Properties

M.Wt	634.10
Formula	C36H24ClNO6S
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	5-(N-((3'-chloro-[1,1'-biphenyl]-4-yl)methyl)-N-(4-((4-hydroxyphenyl)ethynyl)phenyl)sulfamoyl)benzofuran-2-carboxylic acid

References

1. Liang X, et al. J Med Chem. 2026 May 14;69(9):11167-11191.

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PTPRO-IN-1 (Compound 30k)

Biological Activity

Physicochemical Properties

References

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