PTPRO inhibitor GP03

Chemical Structure : PTPRO inhibitor GP03

Catalog No.: PC-28603Not For Human Use, Lab Use Only.

PTPRO inhibitor GP03 is a potent, selective, competitiveinhibitor of protein tyrosine phosphatase receptor type O (PTPRO) with IC50 of 2.89 uM, Ki of 2.64 uM.

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Biological Activity

PTPRO inhibitor GP03 is a potent, selective, competitiveinhibitor of protein tyrosine phosphatase receptor type O (PTPRO) with IC50 of 2.89 uM, Ki of 2.64 uM.

Physicochemical Properties

M.Wt	527.76
Formula	C24H16BrClN2O5
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	(Z)-4-((2-bromo-4-((1-(3-chlorophenyl)-2,5-dioxoimidazolidin-4-ylidene)methyl)phenoxy)methyl)benzoic acid

References

1. Hou X, et al. J Cancer. 2021 Oct 30;12(24):7445-7453.

2. Xuben Hou, et al. J Chem Inf Model. 2018 Nov 26;58(11):2331-2342.

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