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Perindoprilat

Chemical Structure : Perindoprilat

CAS No.: 95153-31-4

Perindoprilat (S 9780)

Catalog No.: PC-28032Not For Human Use, Lab Use Only.

Perindoprilat (S 9780) is a potent, competitive inhibitor of angiotensin-converting enzyme (ACE), inhibits guinea pig plasma ACE with IC50 of 2.4 nM, the active metabolite of perindopril.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Perindoprilat (S 9780) is a potent, competitive inhibitor of angiotensin-converting enzyme (ACE), inhibits guinea pig plasma ACE with IC50 of 2.4 nM, the active metabolite of perindopril.

Physicochemical Properties

M.Wt 340.42
Formula C17H28N2O5
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(2S,3aS,7aS)-1-((S)-2-(((S)-1-Carboxybutyl)amino)propanoyl)octahydro-1H-indole-2-carboxylic acid

References

1. Laubie M, et al. J Cardiovasc Pharmacol. 1984 Nov-Dec;6(6):1076-82.

2. Richer C, et al. J Cardiovasc Pharmacol. 1986 Mar-Apr;8(2):346-57.

3. Unger T, et al. Cardiovasc Pharmacol. 1986 Mar-Apr;8(2):276-85.

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