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Chemical Structure : Pibrentasvir
Catalog No.: PC-63073Not For Human Use, Lab Use Only.
Pibrentasvir (ABT-530) is a novel and pan-genotypic HCV NS5A inhibitor with EC50 of 1.4-5.0 pM against HCV replicons containing NS5A genotypes 1-6.
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Pibrentasvir (ABT-530) is a novel and pan-genotypic HCV NS5A inhibitor with EC50 of 1.4-5.0 pM against HCV replicons containing NS5A genotypes 1-6; demonstrates potent antiviral activity and acceptable safety during 3-day monotherapy in patients with HCV genotype 1 infection, with or without compensated cirrhosis.
HCV Infection
Phase 2 Clinical
| M.Wt | 1113.2 | |
| Formula | C57H65F5N10O8 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Lawitz EJ, et al. Antimicrob Agents Chemother. 2015 Dec 28;60(3):1546-55.
2. Poordad F, et al. Liver Int. 2016 Aug;36(8):1125-32.
3. Ng TI, et al. Antimicrob Agents Chemother. 2017 Apr 24;61(5). pii: e02558-16.
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