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Chemical Structure : Piericidin A
CAS No.: 2738-64-9
Catalog No.: PC-20782Not For Human Use, Lab Use Only.
Piericidin A is a natural insecticide isolated from the spore forming bacterium Streptomyces mobaraensis, Piericidin A is a mitochondrial NADH-ubiquinone oxidoreductase (complex I) inhibitor.
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Piericidin A is a natural insecticide isolated from the spore forming bacterium Streptomyces mobaraensis, Piericidin A is a mitochondrial NADH-ubiquinone oxidoreductase (complex I) inhibitor.
Piericidin A is a potent neurotoxin and inhibits mitochondrial respiration by disrupting the electron transport system through its action on NADH-ubiquinone reductase.
Piericidin A is a potential quorum-sensing inhibitor that suppresses the expression of the virulence genes of Erwinia carotovora subsp. atroseptica (Eca).
| M.Wt | 415.57 | |
| Formula | C25H37NO4 | |
| Appearance | Solid | |
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| Solubility |
10 mM in DMSO |
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1. Bridges HR, et al. Nat Commun. 2020 Oct 16;11(1):5261.
2. Baradaran R, et al. Nature. 2013;494:443–448.
3. Horgan DJ, et al. J. Biol. Chem. 1968;243:5967–5976.
4. i Eun Kang, et al. Microbiol Res. 2016 Mar;18
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