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Pim1/AKK1-IN-1

Chemical Structure : Pim1/AKK1-IN-1

CAS No.: 1093222-27-5

Pim1/AKK1-IN-1 (LKB1/AAK1 dual inhibitor)

Catalog No.: PC-42554Not For Human Use, Lab Use Only.

Pim1/AKK1-IN-1 is a potent, multikinase inhibitor with Kd of 35/53/75/380 nM for Pim1/AKK1/MST2/LKB1 respectively, and also inhibits MPSK1 and TNIK.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Pim1/AKK1-IN-1 is a potent, multikinase inhibitor with Kd of 35/53/75/380 nM for Pim1/AKK1/MST2/LKB1 respectively, and also inhibits MPSK1 and TNIK.

Physicochemical Properties

M.Wt 339.3501
Formula C20H13N5O
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

3-Pyridinecarboxamide, N-[5-(4-cyanophenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]-

References

1. Bamborough P, et al. J Med Chem. 2008 Dec 25;51(24):7898-914.

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