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Profilin1 inhibitor UP-6

Chemical Structure : Profilin1 inhibitor UP-6

CAS No.:

Profilin1 inhibitor UP-6

Catalog No.: PC-26095Not For Human Use, Lab Use Only.

Profilin1 inhibitor UP-6 is a specific small molecule inhibitor of Actin-binding protein profilin1 (Pfn1), inhibits Pfn1-actin interaction and tumor angiogenesis.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

Profilin1 inhibitor UP-6 is a specific small molecule inhibitor of Actin-binding protein profilin1 (Pfn1), inhibits Pfn1-actin interaction and tumor angiogenesis.

Physicochemical Properties

M.Wt 348.37
Formula C18H19F3N4
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

4,4'-((4-(trifluoromethyl)phenyl)methylene)bis(3,5-dimethyl-1H-pyrazole)

References

1. Gau D, et al. Exp Eye Res. 2021 Dec;213:108861.

2. Gau D, et al. J Biol Chem. 2025 Dec 10:111033.

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