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Propofol

Chemical Structure : Propofol

CAS No.: 2078-54-8

Propofol

Catalog No.: PC-70280Not For Human Use, Lab Use Only.

A widely used general anesthetic to induce and maintain anesthesia.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

A widely used general anesthetic to induce and maintain anesthesia; influences ligand-gated channels, including the GABAA receptor and others; also inhibits conventional kinesin-1 KIF5B and kinesin-2 KIF3AB and KIF3AC, causing a significant reduction in the distances that these processive kinesins can travel without an effect on velocity (EC50<100 nM).

Physicochemical Properties

M.Wt 178.271
Formula C12H18O
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

Phenol, 2,6-diisopropyl- (6CI,8CI)

References

1. Bensel BM, et al. Proc Natl Acad Sci U S A. 2017 May 23;114(21):E4281-E4287.

2. Jin WZ, et al. Eur J Pharmacol. 2016 Oct 5;788:37-44.

3. Eaton MM, et al. Curr Neuropharmacol. 2016;14(7):772-80.

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