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Pyrazinib

Chemical Structure : Pyrazinib

CAS No.: 200417-97-6

Pyrazinib (Pyrazinib P3;Pyrazinib (P3))

Catalog No.: PC-36026Not For Human Use, Lab Use Only.

Pyrazinib (Pyrazinib (P3)) is a pyrazine phenol small molecule drug with anti-angiogenic and anti-metabolic activity in-vivo in zebrafish and in-vitro isogenic models of OAC radioresistance.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

Pyrazinib (Pyrazinib (P3)) is a pyrazine phenol small molecule drug with anti-angiogenic and anti-metabolic activity in-vivo in zebrafish and in-vitro isogenic models of OAC radioresistance; significantly inhibited blood vessel development in zebrafish, significantly reduced measures of oxidative phosphorylation and glycolysis in isogenic model of OAC radioresistance; a novel therapeutic radiosensitiser in Oesophageal adenocarcinoma (OAC).

Physicochemical Properties

M.Wt 198.225
Formula C12H10N2O
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(E)-2-(2-Pyrazin-2-yl-vinyl)-phenol

References

1. Buckley AM, et al. Cancer Lett. 2019 Jan 18. pii: S0304-3835(19)30021-7.

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