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Chemical Structure : Pyrimidinone 8
Catalog No.: PC-61214Not For Human Use, Lab Use Only.
Pyrimidinone 8 is a novel allosteric, non-competitive divalent metal transporter-1 (SLC11A2/DMT1) inhibitor with Ki of 20 uM.
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Pyrimidinone 8 is a novel allosteric, non-competitive divalent metal transporter-1 (SLC11A2/DMT1) inhibitor with Ki of 20 uM; does not affect hDMT1 cell surface expression and shows no dependence on extracellular pH.
| M.Wt | 204.233 | |
| Formula | C10H12N4O | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Montalbetti N, et al. Biochem Pharmacol. 2015 Aug 1;96(3):216-24.
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