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RF03176

Chemical Structure : RF03176

CAS No.: 685123-50-6

RF03176 (RF 03176)

Catalog No.: PC-20301Not For Human Use, Lab Use Only.

RF03176 is a selective AQP9 inhibitor with IC50 of 1.3 uM (inhibition of CHO-AQP9 cell water permeability).

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

RF03176 is a selective AQP9 inhibitor with IC50 of 1.3 uM (inhibition of CHO-AQP9 cell water permeability).
RF03176 shows little to no activity against AQP3, AQP7, and AQP8.

Physicochemical Properties

M.Wt 270.31
Formula C13H10N4OS
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

1-(benzo[d][1,2,3]thiadiazol-6-yl)-3-phenylurea

References

1. Sabina Jelen, et al. J Biol Chem. 2011 Dec 30;286(52):44319-25.

2. Sören J Wacker, et al. Mol Membr Biol. 2013 May;30(3):246-60.

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