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Chemical Structure : RG13022
CAS No.: 136831-48-6
Catalog No.: PC-42386Not For Human Use, Lab Use Only.
A potent EGFR inhibitor that inhibits EGFR autophosphorylation with IC50 of 5 uM in cell-free assays.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $88 | In stock | |
| 50 mg | $320 | In stock | |
| 100 mg | $512 | In stock |
Bulk size, bulk discount!
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A potent EGFR inhibitor that inhibits EGFR autophosphorylation with IC50 of 5 uM in cell-free assays; suppresses not only EGF-stimulated cancer cell proliferation in vitro but also tumor growth in nude mice; inhibits cell proliferation of gastric cancer cell lines.
| M.Wt | 266.29456 | |
| Formula | C16H14N2O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
DMSO: 10 mM |
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| Chemical Name/SMILES |
3-Pyridineacetonitrile, α-[(3,4-dimethoxyphenyl)methylene]- |
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1. Yoneda T, et al. Cancer Res. 1991 Aug 15;51(16):4430-5.
2. McLeod HL, et al. Br J Cancer. 1996 Dec;74(11):1714-8.
3. McLaughlin M, et al. Int J Oncol. 1996 Mar;8(3):589-96.
4. Xian W, et al. Cell Growth Differ. 1995 Nov;6(11):1447-55.
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