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Chemical Structure : RG7713
CAS No.: 920022-47-5
Catalog No.: PC-60078Not For Human Use, Lab Use Only.
RG7713 (RO5028442, RG-7713) is a potent, highly selective, brain-penetrant vasopressin 1a (hV1a) antagonist with Ki of 1 nM.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $258 | In stock | |
| 10 mg | $388 | In stock | |
| 25 mg | $558 | In stock | |
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RG7713 (RO5028442, RG-7713) is a potent, highly selective, brain-penetrant vasopressin 1a (hV1a receptor) antagonist with Ki of 1 nM, shows no activiity on hV2 receptor (Ki>30 uM)。
RG7713 (RO5028442) displays moderate mouse affinity and excellent selectivity versus hV2 and hOT receptors.
| M.Wt | 437.97 | |
| Formula | C25H28ClN3O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
(6-Chloro-1-(2-(dimethylamino)ethyl)indol-3-yl)-spiro(1H-isobenzofuran-3,4'-piperidine)-1'-yl-methanone |
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1. Ratni H, et al. J Med Chem. 2015 Mar 12;58(5):2275-89.
2. Umbricht D, et al. Neuropsychopharmacology. 2017 Aug;42(9):1914-1923.
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