ROR1 inhibitor 9i

Chemical Structure : ROR1 inhibitor 9i

Catalog No.: PC-24711Not For Human Use, Lab Use Only.

ROR1 inhibitor 9i is a potent, selective inhibitor of receptor tyrosine kinase-like orphan receptor ROR1, binds the intracellular kinase domain with KD of 17.2 nM, inhibits ROR1 kinase activity with IC50 of 255 nM.

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Biological Activity

Physicochemical Properties

M.Wt	493.56
Formula	C30H27N3O4
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	3-((4'-Acetamido-[1,1'-biphenyl]-3-yl)amino)-N-(2,3-dihydrobenzo[b] [1,4]dioxin-6-yl)-4-methylbenzamide

References

1. Qingquan Zheng, et al. Eur J Med Chem. 2025 Sep 15:294:117755.

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